2017-12-15 16:53:532025-05-06 12:38:41
locus
BSU17850
BSU_17850
geneLength
615
618
ec
outlinks
bsu
BSU17850
BSU_17850
The protein
Catalyzed reaction/ biological activity
Represses ''[[gene|uvrB]], [[gene|bstG]], [[gene|tagC]], [[gene|recA]]'' genes and itself by binding to the 14 bp palindromic sequence 5'-CGAACNNNNGTTCG-3'. In the presence of single-stranded DNA, [[protein|RecA]] interacts with [[protein|LexA]] causing an autocatalytic cleavage which disrupts the DNA-binding part of [[protein|LexA]], leading to derepression of the SOS regulon and eventually DNA repair. (according to Swiss-Prot)
Represses ''[[gene|uvrB]], [[gene|bstG]], [[gene|tagC]], [[gene|recA]]'' genes and itself by binding to the 14 bp palindromic sequence 5'-CGAACNNNNGTTCG-3'. In the presence of single-stranded DNA, [[protein|RecA]] interacts with [[protein|LexA]] causing an autocatalytic cleavage which disrupts the DNA-binding part of [[protein|LexA]], leading to derepression of the SOS regulon and eventually DNA repair (according to UniProt)
Hydrolysis of Ala-|-Gly bond in repressor LexA (according to UniProt)
The protein
Protein family
peptidase S24 family (according to Swiss-Prot)
peptidase S24 family (single member, according to UniProt)
References
Original publications
The protein
Paralogous protein(s)
[[this]]
The protein
additional information
information on binding sites can be found in the [http://www.prodoric2.de/detail.php?acc=MX000025 PRODORIC2 database]